Resumen del artículo

Evaluación global sobre la incidencia de la Injuria Renal Aguda (IRA) que requiere terapia de reemplazo renal (TRR) en la Provincia de Santa Fe y sus resultados.

Carlino MC; Avila R; Monje L; Mantello C; Taurizano N; Ferragut N; Fernández M; Bragado J; Josa P; De Prato J; Dip L; Chapelet A; Fiorilli F; Cuestas M; Alles A

MÉTODOS
Estudio prospectivo, transversal, observacional, multicéntrico en mayores de 14 años con diagnóstico
de IRA con TRR en 2017. Comparación con datos previos (año 2001).
RESULTADOS
125 pacientes registrados; 0,27% de internaciones totales. 72% varones, edad 46,68 años; comorbilidades
en 74%, internación en unidad de cuidados críticos (UCC) 90%; compromiso extra renal (CER) 80,6%. 100%
UF controlada, agua tratada, buffer bicarbonato y membrana biocompatible. Hemodiálisis intermitente
(HDI) 76%, diálisis lenta (SLED) 11%, técnicas continuas 13%. Vivos en última sesión: 49,6% evolución a
diálisis crónica: 15,87%. Mortalidad en última sesión: 40,6%; 30 días: 55,2%; 270 días: 62,4%. Mortalidad
mayor (p < 0,05) en CER (55.36%) vs IRA aislada (16,67%). Respecto a 2001, aumentaron los efectores (2
vs 6), la cantidad de pacientes (181,2 vs 85,18 ppm), la mayor proporción (p<0,05) de pacientes graves
(UCC: 90,4% vs 59,68%) y compromiso extra renal (IRA aislada 10,4% vs 34%). Hubo menor mortalidad
(p<0,05) en totales (49,6% vs 65,65%) y graves (UCC: 54,87% vs 81,08%; CER: 55,36% vs 88,37%) y similar
en IRA aislada (23.08% vs 22.22%). Se incorporaron técnicas lentas y continuas. Mejoró la calidad de HDI:
100% UF controlada y membrana biocompatible vs 77% y 38%, respectivamente.
CONCLUSIONES
Aumentó la cantidad de pacientes dializados y la proporción de criticidad y compromiso extra renal.
Descendió la mortalidad. Aumentó el número de efectores con TRR, mejoró la infraestructura, se
incorporaron técnicas continuas.

INTRODUCTION
Chronic kidney disease (CKD) is associated with the presence of cognitive impairment. There is a need to
identify cognitive impairment in older adults with CKD, in order to carry out an adequate treatment prior
to the start of dialysis. In a study conducted in Colombia, the overall prevalence of cognitive impairment
was 51% (95% CI 44.7- 57.2), with mild cognitive impairment in 35.9% of patients.

OBJECTIVE
To carry out a subanalysis in a group of patients ≥ 55 years of age, with Chronic Kidney Disease Stage 3 and
4, in whom slight cognitive alterations were identified and to establish which of the domains evaluated in
the NEUROPSI test are more compromised.
METHODS
Cross-sectional study. We included 85 patients ≥ 55 years of age, with stage 3 and 4 chronic kidney disease
with mild cognitive impairment in the NEUROPSI test. Descriptive statistics summarized the qualitative
variables with absolute and relative frequencies.
RESULTS
The highest number of failures was observed in verbal semantic (100%) and phonological (92.68%)
verbal fluency tests, followed by sequencing with 88.57%, right hand 74.12% and left hand 62.35% , and
word learning with 52.94%, the realization of the semicomplex figure with 51.
CONCLUSIONS
The executive functions are affected in the CKD, this suggests the need to perform studies with greater
power to determine the factors that mediate its early appearance and contribute to its prevention.




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